Neurosurgery and Neuroscience

Omega 3 and 6 are different types of PUFA having distinct effects on human systems. EFA is most debatable and important nowadays while studying nutritional role of lipids and its effects in physiology. This oral presentation is to focus on recent advances in importance of ratio (omega 6: omega 3) for clinical purposes physiologically. Omega 3 and Omega 6 compete for enzymes to produce signaling molecules, to modulate gene expression and to consolidate cell-membrane. The ratio of omega 6 to omega 3 is of importance according to various studies and its effects on nervous system physiologically, which may differ for different tissues or functions. Many hypothesis and various mechanisms are discussed herewith in context to BBB, membrane fluidity, myelin sheath, neurotransmitters etc. As a researcher it is studied for physiology of Learning, memory, sleep, early development, aging, and stress with EFA. Results conclude that 4:1 ratio has protective and stabilizing effects on neuron and its functions.The ratio may be a key factor in modulating behavioral, developmental, pharmacological effects of lipids.